Factores asociados a la salud y el bienestar en adultos mayores centenarios / Factors associated with health and well-being in centenarian older adults

Introducción: Con el aumento del nivel de vida y la mejora de los sistemas de salud no es raro alcanzar edades extremas de la vida. A inicios del año 2019, en la provincia Pinar del Río, se declararon 109 centenarios; de ellos, 9 correspondían al municipio Los Palacios, donde se mostró un incremento de 3 individuos en comparación con el año precedente. Objetivo: Caracterizar clínica y funcionalmente a los adultos mayores centenarios del territorio. Métodos: Se realizó un estudio observacional descriptivo de corte transversal en el municipio Los Palacios en el período enero-marzo de 2019. Población objeto de estudio: 9 centenarios, a quienes se les aplicó una encuesta estructurada, el índice de Katz y el test de calidad de vida MGH. Se respetaron los criterios de inclusión y los principios de la ética médica. Resultados: Predominó la edad entre 100 y 104 años, el sexo masculino, el color de la piel blanca, la viudez, la convivencia con los hijos, el consumo de café y el déficit sensorial. Todos realizaron actividad física y sus hábitos alimenticios fueron saludables a lo largo de la vida. La mayoría no tuvo criterio de polifarmacia. En la evaluación funcional se analizó la calidad de vida y las alteraciones en las actividades básicas de la vida diaria. Conclusiones: El envejecimiento exitoso en las personas centenarias se caracterizó por tener buena salud percibida y cognitiva, mantener una actitud optimista ante la vida, buena red de apoyo social familiar, antecedentes de familiares longevos y estilos de vida saludables(AU)

Introduction: With the increase in living standards and the improvement of health systems, it is not unusual to reach extreme ages of life. At the beginning of 2019, in Pinar del Río Province, 109 centenarians were reported; of them, 9 belonged to Los Palacios Municipality, where there was an increase of 3 individuals compared to the previous year. Objective: To characterize clinically and functionally the centenarian adults from the territory. Methods: A cross-sectional, descriptive and observational study was carried out in Los Palacios Municipality, in the period from January to March 2019. The study population consisted of 9 centenarians, to whom a structured survey was applied: Katz index and MGH quality of life test. The inclusion criteria and the principles of medical ethics were respected. Results: There was a predominance of ages 100-104 years, the male sex, white skin color, widowhood, the condition of sharing house with children, coffee consumption and sensory deficit. All the patients did physical activity and their eating habits were healthy throughout life. Most of them did not have polypharmacy criteria. Regarding their functional assessment, quality of life and alterations in basic activities of daily life were analyzed. Conclusions: Successful aging in centenarians showed that they have good health, both cognitive and perceived, maintain an optimistic attitude towards life, have a good family social support network, a history of long-lived family members, and healthy lifestyles(AU)

Funcionalidade de idosos ativos no centro de convivência da terceira idade em Teresina / Functionality of elderly activities at the third age living center in Teresina

Este artigo tem por objetivo avaliar a funcionalidade dos idosos que estão cadastrados em um Centro de Convivência da Terceira Idade. Trata-se de uma pesquisa descritiva, do tipo quantitativa e transversal, realizada com 51 idosos. O instrumento de avaliação foi constituído da investigação das características sociodemográficas, da funcionalidade através do Índice de Katz, escala de Lawton e nível de Atividade e Participação, de acordo com a Classificação Internacional de Funcionalidade, Incapacidade e Saúde (CIF). A análise estatística foi realizada no software BioState versão 5.4, utilizando a média, desvio-padrão, o teste de correlação de Pearson para dados paramétricos e o de associação do Qui-quadrado e Spearman para os dados não paramétricos. Na avaliação das características sociodemográficas, verificou-se que 80,4% dos idosos eram do sexo feminino, com média de idade de 70.8 (±5,5) anos, viúvos (n=20) e recebiam aposentadoria (n=31). Em relação à funcionalidade, 100% dos idosos apresentaram independência para a maioria das Atividades Básicas de Vida Diária (ABVD ́s),porém observou-se prevalência importante (9,8%) de incontinência urinária presente nas idosas do estudo. Para a realização das Atividades Instrumentais de Vida Diária (AIVD ́s), a maioria dos idosos apresentaram independência, contudo foi identificada prevalência considerável de idosos com alguma dependência (parcial ou total) para sua execução. No que se refere à classificação da funcionalidade pela CIF, a maioria dos códigos utilizados para classificação da funcionalidade dos idosos apresentou em comum o qualificador 0. Constatou-se que a participação dos idosos em um Centro de Convivência promove maior independência e autonomia aos idosos, demonstrando a sua importância.(AU)

This article aims to evaluate the functionality of the elderly who are registered in a Community Center for the Elderly. This is a descriptive, quantitative and cross-sectional study conducted with 51 elderly people. The evaluation instrument consisted of the investigation of sociodemographic characteristics, functionality through the Katz Index, Lawton scale and level of Activity and Participation, according to the International Classification of Functionality, Disability and Health (CIF). Statistical analysis was performed using the BioState software version 5.4, using the mean, standard deviation, Pearson's correlation test for parametric data and the Chi-square and Spearman association test for nonparametric data. In the assessment of sociodemographic characteristics, it was found that 80.4% of the elderly were female, with an average age of 70.8 (± 5.5) years, widowed (n = 20) and receiving retirement (n = 31). Regarding functionality, 100% of the elderly were independent for most of the Basic Activities of Daily Living (BADLs), but there was an important prevalence (9.8%) of urinary incontinence present in the elderly of the study. For the performance of Instrumental Activities of Daily Living (IADLs), the majority of the elderly showed independence, however a considerable prevalence of elderly people with some dependence (partial or total) for their execution was identified. Regarding the classification of functionality by the ICF, most of the codes used to classify the functionality of the elderly had the qualifier 0 in common. It was found that the participation of the elderly in Community Center promotes greater independence and autonomy for the elderly, demonstrating its importance.(AU)

Salud mental de los mexicanos durante la pandemia de COVID-19 / Mental health of the Mexican population during the COVID-19 pandemic

Resumen Introducción: La pandemia de COVID-19 también ha afectado la salud mental. Objetivo: Evaluar la salud mental de la población mexicana durante la pandemia de COVID-19 mediante la medición de síntomas de estrés, depresión, ansiedad, insomnio y resiliencia. Métodos: Estudio observacional, descriptivo y transversal. Con una encuesta se recabaron datos sociodemográficos y se aplicaron la Depression Anxiety and Stress Scale 21 (DASS 21), la Escala Atenas de Insomnio y la Escala de Resiliencia 14 Ítems (RS-14). Se obtuvieron medidas de tendencia central y de dispersión en las variables cuantitativas, así como frecuencias en las cualitativas. En el análisis bivariado se utilizó la prueba de χ2; el nivel alpha fue 0.05. Resultados: Se analizaron 1667 individuos con edad media de 33.78 ± 10.79 años. En la DASS 21 se encontró una media de 9.7 puntos (normal), 7.10 para ansiedad (normal) y 6.73 para depresión (normal). La Escala Atenas de Insomnio presentó una media de 9.33 puntos (alteración moderada) y la RS-14, 69.13 (resiliencia alta). Conclusiones: La intensidad de la sintomatología fue menor a la esperada en comparación con la registrada en otras poblaciones, probablemente por la alta resiliencia de la población mexicana.

Abstract Introduction: The COVID-19 pandemic has also affected mental health. Objective: To evaluate Mexican population mental health during the COVID-19 pandemic by measuring symptoms of stress, depression, anxiety and insomnia, as well as resilience. Methods: Cross-sectional, descriptive, observational study. A survey was carried out to collect sociodemographic data, and the Depression Anxiety and Stress Scale 21 (DASS 21), Athens Insomnia Scale and the 14-item Resilience Scale (RS-14) were applied. Central tendency and dispersion measures were obtained for quantitative variables and frequencies for qualitative variables. The chi-square test was used for bivariate analysis; alpha level was 0.05. Results: 1,667 individuals with a mean age of 33.78 ± 10.79 years were analyzed. On DASS 21, a mean of 9.7 points (normal) was found, as well as 7.10 for anxiety (normal) and 6.73 for depression (normal). In the Athens Insomnia Scale, a mean of 9.33 points (moderate alteration), and in the RS-14 scale, 69.13 points (high resilience) were obtained. Conclusions: Symptoms' intensity was lower than expected in comparison with that recorded in other populations, probably due to the high levels of resilience of the Mexican population.

Depresión asociada a condiciones sociales, familiares y dependencia física en un hospital de Quito / Depression associated with social and family conditions and physical dependence in a Quito hospital

INTRODUCCIÓN. La depresión es frecuente y variada en el adulto mayor. Se asocia a varias condiciones sociales, económicas y físicas. OBJETIVO. Determinar la asociación e interacción entre la depresión y las condiciones sociales, familiares y dependencia física en adultos ma-yores. MATERIALES Y MÉTODOS. Se realizó un estudio descriptivo, transversal. Población de 474 adultos mayores deprimidos y muestra de 390 que acudieron a la consulta externa del Hospital de Especialidades Carlos Andrade Marín de Quito en el año 2018. Se utilizó la MINI Entrevista Neuropsiquiátrica Internacional para el diagnóstico de depresión y las escalas de Katz, Socio-familiar de Gijón y datos demográficos. La asociación se estableció mediante chi cuadrado de homogeneidad, cálculo de Odds de prevalencia y, para la interacción de variables, modelos de regresión logística binaria. Los cálculos estadísticos se realizaron en el programa estadístico International Business Machines Statistical Package for the Social Sciences. RE-SULTADOS. La prevalencia de depresión fue de 26,4% (103; 390) con 58,0% (60; 103) de episodio depresivo leve. La depresión guardó relación con la pertenencia a grupos sociales, dependencia y situación de riesgo social. En la regresión logística binomial con las variables socio-familiares el mayor peso cayó sobre las malas relaciones sociales (Exp B: 1,8); en el modelo con las variables significativas, en la dependencia (Exp B: 2,6). Los modelos clasifica-ron de manera correcta a los deprimidos. Las variables se tornaron significativas (p<0,05) al interactuar con riesgo y problema social. CONCLUSIÓN. Existió asociación entre depresión y dependencia, riesgo social y pertenencia a grupos sociales. El perfil de las personas deprimidas fue de personas dependientes, en riesgo social y que no pertenecían a grupos sociales.

INTRODUCTION. Depression is frequent and diverse in the elderly. It is associated with se-veral social, economic and physical conditions. OBJECTIVE. Determine the association and interaction between depression, social and family conditions and physical dependence in the elderly. MATERIALS AND METHODS. A descriptive, cross-sectional study was carried out. Population of 474 depressed older adults and a sample of 390 who attended the outpatient clinic of the Hospital de Especialidades Carlos Andrade Marín de Quito in 2018. The MINI was used International Neuropsychiatric Interview for the diagnosis of depression and the scales of Katz, Socio-familiar of Gijón and demographic data. The association was established using chi square of homogeneity, calculation of prevalence Odds and, for the interaction of variables, binary logistic regression models. Statistical calculations were performed in the program Statis-tical International Business Machines Statistical Package for the Social Sciences. RESULTS. The prevalence of depression was 26.4% (103; 390) with 58.0% (60; 103) of mild depressive episode. Depression was related to belonging to social groups, dependency and social risk situation. In the binomial logistic regression with the variables socio-family, the greatest weight fell on bad social relationships (Exp B: 1.8); at model with significant variables, in dependence (Exp B: 2.6). The models correctly classified the depressed. The variables became significant (p <0.05) when interact with risk and social problem. CONCLUSION. There was an association between depression and dependency; social risk and belonging to social groups. The profile of depressed people was of dependent people, at social risk who did not belong to social groups.

Quality of life and psychometric evaluation of patients diagnosed with irritable bowel syndrome: an observational cohort study

ABSTRACT BACKGROUND: Very few data are available for evaluating health-related quality of life among people with irritable bowel syndrome (IBS) and even fewer data are available in relation to anxiety and depression status among these patients. OBJECTIVES: To evaluate the quality of life, anxiety and depression status of patients with IBS. DESIGN AND SETTING: Observational cohort study conducted in a tertiary-care university hospital. METHODS: Patients who had recently been diagnosed with IBS and who had been followed up for IBS-specific treatment for at least three months were included. A quality of life (QoL) survey, the Beck Anxiety Index (BAI) and the Hamilton Depression Index (HAM-D) were applied to the patients. RESULTS: In total, 274 patients with IBS were included in the study cohort. These patients presented very high baseline scores for anxiety and depression, and very poor QoL results. CONCLUSION: Our study showed that IBS had a very high impact on these patients, regarding their anxiety and depression levels, alongside very poor results relating to quality of life.

Investigating gender differences for effectiveness and side effects of varenicline during smoking cessation treatment

SUMMARY Varenicline is a useful pharmacological option for smoking cessation. Unfortunately, there is a lack of studies on its effectiveness, retention, and side effects in low- and middle-income countries. The present study aimed to investigate gender differences regarding these outcomes in a Brazilian clinical sample (n = 124). The 12-week treatment protocol included six consultations with a psychiatrist and six sessions of cognitive-behavioral therapy. All subjects received varenicline on the first evaluation, following the standard posology for 12 weeks and instructions to stop smoking after the second week of treatment. Both Mini-International Neuropsychiatric Interview (MINI) Plus and Fagerstrom Test for Nicotine Dependence were applied at baseline. The UKU-Side Effects Rating Scale was administered at weeks 3, 7, and 11, and the Questionnaire of Smoking Urges-Brief at weeks 1, 5, and 9 to ascertain the side effects of the medication and craving, respectively. At the end of the 12-week treatment, abstinence was biochemically assessed. At months 6 and 12 after the treatment, follow-up telephone interviews were conducted to access nicotine abstinence. Short- and long-term abstinence and retention rates did not differ between genders. However, women presented more side effects than men, especially in the second half of the treatment. Increased dream activity, reduced duration of sleep, constipation, and weight loss were the most notable side effects. Despite women reporting more side effects than men, this difference did not influence the treatment success rates.

RESUMO A vareniclina é uma opção farmacológica útil para a cessação do tabagismo. Infelizmente, há uma ausência de estudos sobre a eficácia, retenção e efeitos colaterais para este medicamento em países de baixa e média renda. O presente estudo teve como objetivo investigar diferenças entre gênero em relação a esses desfechos em uma amostra clínica brasileira (n = 124). O protocolo de tratamento de 12 semanas incluiu seis consultas com um psiquiatra e seis sessões de psicoterapia cognitivo-comportamental. Todos os indivíduos receberam vareniclina na primeira avaliação, seguindo a posologia padrão por 12 semanas e instrução para parar de fumar a partir da segunda semana de tratamento. Tanto o Mini-International Neuropsychiatric Interview (MINI) Plus quanto o Teste de Fagerstrom para Dependência de Nicotina foram aplicados no início do estudo. A escala de efeitos colaterais (UKU-Side Effects Rating Scale) foi aplicada nas semanas 3, 7 e 11, e o Questionário Breve de Fissura (Questionnaire of Smoking Urges-Brief) nas semanas 1, 5 e 9 para investigar os efeitos colaterais da medicação e fissura, respectivamente. No final do tratamento de 12 semanas, a abstinência foi avaliada bioquimicamente. Aos 6 e 12 meses após o tratamento, foram realizadas entrevistas telefônicas de acompanhamento para acessar a abstinência de nicotina. As taxas de abstinência e retenção de curto e longo prazo não diferiram entre gêneros. No entanto, as mulheres apresentaram mais efeitos colaterais do que os homens, principalmente na segunda metade do tratamento. Aumento da atividade dos sonhos, redução da duração do sono, constipação e perda de peso foram os efeitos colaterais mais notáveis. Apesar de as mulheres relatarem mais efeitos colaterais que os homens, essa diferença não influenciou as taxas de sucesso do tratamento.

Personality disorder and functioning in major depressive disorder: a nested study within a randomized controlled trial

Objective: This study aimed to determine if personality disorder (PD) predicted functional outcomes in patients with major depressive disorder (MDD). Methods: Data (n=71) from a double-blind, randomized, placebo-controlled 12-week trial assessing the efficacy of 200 mg/day adjunctive minocycline for MDD were examined. PD was measured using the Standardized Assessment of Personality Abbreviated Scale. Outcome measures included Clinical Global Impression - Improvement (CGI-I), Quality of Life Enjoyment and Satisfaction Questionnaire (Q-LES-Q), Social and Occupational Functioning Scale (SOFAS), and Range of Impaired Functioning (RIFT). Analysis of covariance was used to examine the impact of PD (dichotomized factor [≥ 3] or continuous measure) on the outcome measures-treatment group correlation. Results: PD was identified in 69% of the sample. After adjusting for age, sex, and baseline scores for each of the outcome measures, there was no significant difference between participants with and without PD on week 12 scores for any of the outcome measures (all p > 0.14). Conclusion: In this secondary analysis of a primary efficacy study, PD was a common comorbidity among those with MDD, but was not a significant predictor of functional outcomes. This study adds to the limited literature on PD in randomized controlled trials for MDD. Clinical trial registration: ACTRN12612000283875.

Incidence of depression in patients with hepatitis C treated with direct-acting antivirals

Objective: Depression has been associated with hepatitis C, as well as with its treatment with proinflammatory cytokines (i.e., interferon). The new direct-acting antiviral agents (DAAs) have minimal adverse effects and high potency, with a direct inhibitory effect on non-structural viral proteins. We studied the incidence and associated factors of depression in a real-life prospective cohort of chronic hepatitis C patients treated with the new DAAs. Methods: The sample was recruited from a cohort of 91 patients with hepatitis C, of both sexes, with advanced level of fibrosis and no HIV coinfection, consecutively enrolled during a 6-month period for DAA treatment; those euthymic at baseline (n=54) were selected. All were evaluated through the depression module of the Patient Health Questionnaire (PHQ-9-DSM-IV), at three time points: baseline, 4 weeks, and end-of-treatment. Results: The cumulative incidence (95%CI) of major depression and any depressive disorder during DAA treatment was 13% (6.4-24.4) and 46.3% (33.7-59.4), respectively. No differences were observed between those patients with and without cirrhosis or ribavirin treatment (p > 0.05). Risk factors for incident major depression during DAA treatment included family depression (relative risk 9.1 [1.62-51.1]), substance use disorder (11.0 [1.7-73.5]), and baseline PHQ-9 score (2.1 [1.1-3.1]). Conclusions: The findings of this study highlight the importance of screening for new depression among patients receiving new DAAs, and identify potential associated risk factors.

Chronotype in bipolar disorder: an 18-month prospective study

Objective: Circadian dysregulation plays an important role in the etiology of mood disorders. Evening chronotype is frequent in these patients. However, prospective studies about the influence of chronotype on mood symptoms have reached unclear conclusions in patients with bipolar disorder (BD). The objective of this study was to investigate relationship between chronotype and prognostic factors for BD. Methods: At the baseline, 80 euthymic BD patients answered a demographic questionnaire and clinical scales to evaluate anxiety, functioning and chronotype. Circadian preference was measured using the Morningness-Eveningness Questionnaire, in which lower scores indicate eveningness. Mood episodes and hospitalizations were evaluated monthly for 18 months. Results: Among the BD patients, 14 (17.5%) were definitely morning type, 35 (43.8%), moderately morning, 27 (33.7%) intermediate (neither) and 4 (5%) moderately evening. Eveningness was associated with obesity or overweight (p = 0.03), greater anxiety (p = 0.002) and better functioning (p = 0.01), as well as with mood episodes (p = 0.04), but not with psychiatric hospitalizations (p = 0.82). This group tended toward depressive episodes (p = 0.06), but not (hypo)mania (p = 0.56). Conclusion: This study indicated that evening chronotype predicts a poor prognostic for BD. It reinforces the relevance of treating rhythm disruptions even during euthymia to improve patient quality of life and prevent mood episodes.

Niveles de estrés, ansiedad y depresión en la primera fase del brote del COVID-19 en una muestra recogida en el norte de España / Níveis de estresse, ansiedade e depressão na primeira fase do surto de COVID-19 em uma amostra no norte da Espanha / Stress, anxiety, and depression levels in the initial stage of the COVID-19 outbreak in a population sample in the northern Spain

En marzo de 2020, el virus SARS-CoV-2 procedente de China ha llegado a España y desde el 14 de marzo se ha declarado el estado de alarma en todo el Estado español, llevando al confinamiento a toda la población. La presente investigación se contextualiza en la Comunidad Autónoma Vasca (situada al norte de España). Se han analizado los niveles de estrés, ansiedad y depresión a la llegada del virus y se han estudiado los niveles de sintomatología psicológica según edad, cronicidad y confinamiento. Se ha recogido una muestra de 976 personas y la medición de las variables ansiedad, estrés y depresión se ha hecho mediante la escala DASS (Escala de Depresión, Ansiedad y Estrés). Los resultados demuestran que, aunque los niveles de sintomatología han sido bajos en general al principio de la alarma, la población más joven y con enfermedades crónicas ha referido sintomatología más alta que el resto de población. También se ha detectado un mayor nivel de sintomatología a partir del confinamiento, donde las personas tienen prohibido salir de sus casas. Se prevé que la sintomatología aumentará según vaya transcurriendo el confinamiento. Se defienden intervenciones psicológicas de prevención y tratamiento para bajar el impacto psicológico que pueda crear esta pandemia.

Em março de 2020, o vírus SARS-CoV-2, procedente da China, chegou à Espanha e desde 14 de março está declarado estado de emergência em todo o país, forçando toda a população ao confinamento. O presente estudo foi conduzido no País Basco (norte da Espanha). Foram analisados os níveis de estresse, ansiedade e depressão desde a introdução do vírus e os níveis de sintomas psicológicos segundo idade, comorbidades e confinamento. A amostra foi composta de 976 indivíduos e a medição das variáveis ansiedade, estresse e depressão foi realizada a partir do intrumento DASS (Escala de Depressão, Ansiedade e Estresse). Os resultados mostram que, ainda que os níveis de sintomas tenham sido baixos no início do confinamento, os indivíduos mais jovens e com comorbidades referiram mais sintomas que o restante da população. Também se detectou maior nível de sintomas desde o confinamento, quando a população foi proibida de sair de suas casas. Se prevê aumento dos sintomas conforme o confimaneto continuar. Intervenções psicológicas de prevenção e tratamento são necessárias para diminuir o impacto psicológico causado pela pandemia.

The SARS-CoV-2 virus reached Spain in March 2020, and a nationwide state of alert was declared on March 14th, leading to the confinement of the entire population. The current study was conducted in the Basque Autonomous Community in northern Spain. The authors analyzed stress, anxiety, and depression with the arrival of the virus and the levels of symptoms according to age, comorbidity, and confinement. Levels of anxiety, stress, and depression were measured in a sample of 976 adults, using the DASS scale (Depression Anxiety, and Stress Scale). Although levels of symptoms were generally low at the start of the alert, younger individuals with chronic diseases reported more symptoms than the rest of the population. The study also detected higher levels of symptoms after the stay-at-home order was issued. Such symptoms are predicted to increase as the confinement continues. The authors propose psychological interventions for prevention and treatment in order to mitigate the pandemic's psychological impacts.

Does psychotherapy improve alexithymia? A comparison study among patients with mild or moderate depression

Abstract Background Alexithymia is reported to be a risk factor for depression. Psychotherapy is efficient for treatment of depression. Yet, the effect of psychotherapies on alexithymia is poorly understood. Objectives We aimed to compare Cognitive Behavioral Therapy (CBT), Existential Psychotherapy (ExP) and Supportive Counseling (SUP) for therapeutic efficacy and effect on alexithymia in depression. Methods There were 22 patients for each patient group. Sessions were performed as eight consecutive weekly and following two monthly boosters. Sixty six healthy controls were added. Prior to the sessions, patients received Sociodemographic Data Form, the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-1), Hamilton Depression Rating Scale (HDRS) and 20-item Toronto Alexithymia Scale (TAS-20). The control group received Sociodemographic Data Form, SCID-1 and TAS-20. Patients additionally received HDRS and TAS-20 after their weekly and booster sessions. Results Patients' mean TAS-20 score was greater than of controls, however, it did not have a significant change throughout the study. Mean HDRS scores of ExP and CBT groups were lower than SUP group at the end. Discussion Alexithymia did not improve with psychotherapy. The exception was effect of ExP on externally oriented thinking. Psychotherapies all improved depression. CBT and ExP were more helpful than SUP.

Comparison of quality of life and functionality in type 2 diabetics with and without insulin

SUMMARY INTRODUCTION Type 2 diabetes mellitus compromises physical, psychological, economic, and social life. OBJECTIVES To identify and compare the quality of life, depression, functional performance, and physical activity in patients with type 2 diabetes mellitus who use insulin or not. METHODS A observational, descriptive, cross-sectional, comparative study involving 100 patients (50 use insulin and 50 do not) from a Teaching Hospital. Questionnaires used: Identification and Socioeconomic Profile; SF-36; Hospital Anxiety and Depression Scale; Visual Analogue Scale for Pain; Canadian Occupational Performance Measure, and International Physical Activity Questionnaire. RESULTS Sample composed predominantly by middle-aged, female, married, retired, and with incomplete elementary school individuals. There is impairment in all domains of quality of life, being more intense in functional capacity, physical limitations, pain, social aspects, limitation by emotional aspects, and mental health (P<0.05). There is a significant prevalence of anxiety or depressive symptoms in the groups, especially in those using insulin. However, the occurrence of the corresponding psychiatric disorders is unlikely (P<0.05). There was no significant difference in neuropathic pain between the groups (P=0.2296). Functional impairment is similar in both groups regarding self-care activities (P=0.4494) and productivity (P=0.5759), with a greater deterioration of leisure time in patients on insulin (P=0.0091). Most of them practice physical activity, predominantly walking, with no significant difference when comparing the groups (P>0.05), as well as in the other modalities. CONCLUSION Insulinized patients present greater impairment of functional capacity and socialization, as well as greater neuropathic pain, anxiety, and depressive symptoms.

RESUMO INTRODUÇÃO Diabetes mellitus tipo 2 compromete física, psicológica, econômica e socialmente. OBJETIVOS Identificar e comparar qualidade de vida, depressão, desempenho funcional e exercício físico em pacientes com diabetes mellitus tipo 2 insulinizados ou não. MÉTODOS Estudo individuado, observacional, descritivo, transversal, comparativo envolvendo 100 pacientes (50 utilizam insulina e 50 não) em um hospital escola. Instrumentos utilizados: Ficha de Identificação e Perfil Socioeconômico; SF-36; Escala Hospitalar de Ansiedade e Depressão; Escala Visual Analógica de Dor; Medida Canadense de Desempenho Ocupacional e Questionário Internacional de Atividade Física. RESULTADOS Amostra composta, predominantemente, por indivíduos de meia-idade, sexo feminino, casados, ensino fundamental incompleto e aposentados. Há comprometimento de todos os domínios da qualidade de vida, sendo mais intenso nos insulinizados em capacidade funcional, limitação por aspectos físicos, dor, aspectos sociais, limitação por aspectos emocionais e saúde mental (P<0,05). Importante prevalência de sintomas ansiosos ou depressivos nos grupos, principalmente nos em uso de insulina, porém a ocorrência dos transtornos psiquiátricos correspondentes é improvável (P<0,05). Não houve diferença significativa da DNP entre os grupos (P=0,2296). O prejuízo da funcionalidade é semelhante em relação a atividades de autocuidado (P=0,4494) e produtividade (P=0,5759) nos dois grupos, havendo maior deterioração do lazer em usuários de insulina (P=0,0091). A maioria pratica atividade física, tendo a caminhada a maior adesão, sem diferença significativa ao comparar os grupos (P>0,05), repetindo-se nas demais modalidades. CONCLUSÃO Pacientes insulinizados apresentaram maior prejuízo da capacidade funcional e na socialização, assim como referem maiores dores neuropáticas e sintomas ansiosos e depressivos.

Comparison of patients with migraine and tension-type headache in terms of somatosensory amplification and health anxiety / Estudo comparativo de pacientes com enxaqueca e cefaleia do tipo tensional em relação à amplificação somatossensorial e à ansiedade associada à saúde

ABSTRACT Although it is known that anxiety and depressive disorders frequently accompany migraine and TTH, the role of somatic amplification (SSA) and health anxiety in these diseases is not adequately known. Objective: The aim of this study is to compare SSA and health anxiety in patients with migraine or TTH, and healthy controls and to investigate the relationships between SSA, health anxiety, headache characteristics, anxiety and depressive symptoms. Methods: Fifty-four migraine, 50 TTH patients from the outpatient unit of the neurology department and 53 healthy volunteers were recruited for the study. The somatosensory amplification scale (SSAS), health anxiety inventory, Beck depression (BDI) and anxiety inventory (BAI) were administered to all participants. Results: The SSAS scores were significantly higher in migraineurs compared with the healthy controls. The health anxiety scores were significantly higher in both migraine and TTH groups. The BDI and BAI scores were also significantly higher in migraine and TTH groups compared with the controls. A significant positive correlation was found between headache frequency and BAI scores, the visual analogue scale scores and SSAS and BDI scores in migraineurs. The SSAS scores were also significantly correlated with the BDI and BAI scores in both of the headache groups. A similar correlation was determined with the health anxiety scores. Conclusions: While patients with migraine and TTH evalute, taking into account the SSA and health anxiety may contribute to the prognosis and treatment of these diseases.

RESUMO Embora se saiba que os distúrbios de ansiedade e depressão frequentemente acompanhem a enxaqueca e a TTH, o papel da amplificação somatossensorial (somatosensory amplification, SSA) e da hipocondria nessas doenças ainda não é bem conhecido. Objetivo: O presente estudo faz uma comparação entre pacientes que sofrem de enxaqueca e TTH com um grupo de controle saudável em termos de SSA e hipocondria e investiga a relação entre os achados e as características da cefaleia, a ansiedade e os sintomas depressivos. Métodos: O estudo incluiu 54 pacientes com enxaqueca, 50 pacientes com TTH e 53 voluntários saudáveis que se cadastraram na clínica de neurologia. A escala de amplificação somatossensorial (somatosensory amplification scale, SSAS), o inventário de hipocondria, o Inventário de Depressão de Beck (Beck Depression Inventory, BDI) e o Inventário de Ansiedade de Beck (Beck Anxiety Inventory, BAI) foram aplicados aos participantes. Resultados: Quando comparados com os controles saudáveis, as pontuações da SSAS dos pacientes com enxaqueca foram significativamente maiores, enquanto as pontuações de hipocondria foram significativamente maiores em ambos os grupos de enxaqueca e TTH. As pontuações do BAI e do BDI foram significativamente maiores em ambos os grupos de pacientes que no grupo de controle. No grupo da enxaqueca, foi identificada uma correlação positiva entre frequência de cefaleia e ansiedade, bem como entre a Escala Analógica Visual (EVA), a SSAS e a depressão. Em ambos os grupos de pacientes, a SSA foi correlacionada positivamente com a depressão e a ansiedade, e uma correlação semelhante foi encontrada entre a SSA e a hipocondria. Conclusão: Em avaliações dessas doenças, a hipocondria e a SSA devem ser levadas em consideração, pois se acredita que essa abordagem possa contribuir positivamente para o prognóstico e tratamento da doença.

Improving skin picking diagnosis among Brazilians: validation of the Skin Picking Impact Scale and development of a photographic instrument

Abstract Background Skin picking disorder is a prevalent disorder frequently comorbid with depression and anxiety, which is underdiagnosed mainly by dermatologists. Assessment of skin picking disorder is based on instruments influenced by the awareness about skin picking disorder and comorbid symptoms. To date, there is no validated instrument for Brazilian individuals nor an instrument to evaluate the severity of skin lesions in an objective way. Objectives Validate the Skin Picking Impact Scale for Brazilian Portuguese and create a photographic measurement to assess skin lesions. Methods The sample was assessed through the Skin Picking Impact Scale translated into Brazilian Portuguese, the Hamilton Anxiety Scale, the Beck Depression Inventory, and the Clinical Global Impression Scale. The patients' skin lesions were photographed. Photos were evaluated regarding active excoriation, crust/bleeding, exulceration, and linear lesions. Results There were 63 patients included. The Skin Picking Impact Scale translated into Brazilian Portuguese had good internal consistency (Cronbach's alpha = 0.88), which tests of goodness-of-fit, showing a suitable model. The reliability of photographic measurement was 0.66, with a high internal consistency (Cronbach's alpha = 0.87). Photographic measurement was not correlated with the Skin Picking Impact Scale, the Clinical Global Impression Scale, or comorbid symptoms. Study limitations Lack of a previously validated instrument to evaluate dermatillomania in the Brazilian population for comparison. Conclusion The Skin Picking Impact Scale validated in Brazilian Portuguese is a good instrument to evaluate skin picking disorder. Photographic measurement is a consistent way of assessing skin lesions, but it does not reflect the impact of skin picking disorder on the individual's life.

Desordens mentais e qualidade de vida em pacientes em lista de espera para realização de transplante de fígado / Mental disorders and quality of life in patients awaiting liver transplantation

ABSTRACT BACKGROUND: Liver transplantation is the main therapeutic alternative for patients with advanced liver disease. These patients have high prevalence of psychiatric comorbidities that may negatively interfere in clinical outcomes and quality of life. It is not clear in the literature whether the different etiologies of hepatic disease have the same prevalence of psychiatric disorders. OBJECTIVE: The aim of this study was to investigate whether patients in the liver transplant list showed differences in psychiatric characteristics, medical variables and quality of life among different etiological groups. METHODS: This is a cross-sectional study that evaluates quality of life, psychiatric and clinical comorbidities through the application of validated questionnaires and instruments in 248 patients who were on transplant waiting list from 2010 to 2014, assisted in a University Hospital and in a Private Hospital in Salvador/Bahia, Brazil. The patients were evaluated through the Mini International Neuropsychiatric Interview (M.I.N.I. PLUS 5.0) and Medical Outcomes Short-Form Health Survey (SF-36). RESULTS: The etiology of the most prevalent liver disease was hepatitis C virus. A prevalence of 50.8% of at least one mental disorder was identified. When alcohol abuse/dependence was excluded, the prevalence was 25.8%. Mental health did not show a statistically significant difference in the diverse etiological groups, but a higher prevalence of psychiatric comorbidities was detected among women and younger than 40 years. No cases of psychotic disorders were detected, possibly by exclusion prior to listing. There was no difference in the quality of life domains in the different liver etiological groups. CONCLUSION: A high-prevalence of psychiatric disorders was found among all clinical conditions most associated with indication for liver transplantation. Attention is drawn to the absence of patients with psychotic disorders, which suggests that transplantation may not have been indicated for this group of patients. For these reasons, professionals caring for liver transplant candidates should be highly vigilant for the presence of mental disorders, regardless of the etiology of liver disease. Specialized care is recommended to minimize the early exclusion of patients with no other therapeutic possibilities, as well as care of all people with mental disorders.

RESUMO CONTEXTO: O transplante hepático é a principal alternativa terapêutica para pacientes com doença hepática avançada. Esses pacientes apresentam alta prevalência de comorbidades psiquiátricas que podem interferir negativamente nos desfechos clínicos e qualidade de vida. Não está claro na literatura se as diferentes etiologias de doença hepática têm a mesma prevalência de transtornos psiquiátricos. OBJETIVO: O objetivo deste estudo foi investigar se os pacientes na lista de transplante hepático apresentavam diferenças nas variáveis psiquiátricas, variáveis clínicas e qualidade de vida em diferentes grupos etiológicos. MÉTODOS: Estudo transversal que avalia as comorbidades psiquiátricas e clínicas e as variáveis de qualidade de vida por meio da aplicação de questionários e instrumentos validados em 248 pacientes inseridos em lista de espera para transplante hepático no período de 2010 a 2014, acompanhados no Hospital Universitário Professor Edgard Santos e Hospital Português (Salvador, BA). Os pacientes foram avaliados através da aplicação do Mini International Neuropsychiatric Interview (M.I.N.I. PLUS 5.0) e Medical Outcomes Short-Form Health Survey (SF-36). RESULTADOS: A etiologia da doença hepática mais prevalente foi o vírus da hepatite C. Prevalência de 50,8% de pelo menos um transtorno mental foi identificada. Quando o abuso/dependência de álcool foi excluído, a prevalência foi de 25,8%. A saúde mental não apresentou diferença estatisticamente significante nos diversos grupos etiológicos. Maior prevalência de comorbidades psiquiátricas foi detectada entre mulheres e menores de 40 anos. Não foram detectados casos de transtornos psicóticos, possivelmente pela não inclusão destes pacientes na lista. Não houve diferença nos domínios de qualidade de vida nos diferentes grupos etiológicos. CONCLUSÃO: Uma alta prevalência de transtornos psiquiátricos foi encontrada nos pacientes com todas as condições clínicas mais associadas à indicação de transplante hepático. Chama a atenção a ausência de pacientes com transtornos psicóticos, o que sugere que possivelmente o transplante não tem sido indicado para esse grupo de pacientes. Por esses motivos, os profissionais que cuidam de candidatos ao transplante de fígado devem ser altamente vigilantes para a presença de transtornos mentais, independentemente da etiologia da doença hepática. A atenção especializada é recomendada para os pacientes com transtornos mentais, com minimização de exclusão precoce da lista de pacientes sem outras possibilidades terapêuticas.

Construction and validation of the Adult Stressors Inventory (ASI) / Construção e validação do Inventário de Estressores para Adultos (IE)

Abstract Introduction A great deal of research has been conducted all over the world into stress and its impacts on the health of populations. Objective To develop and validate an instrument for identification of the principal stressors and their magnitude in people who are subject to stress. Method The instrument was constructed on the basis of analysis of 20 interviews conducted with 10 male and 10 female adults with stress according to the Perceived Stress Scale. A total of 46 statements were derived from this analysis, referring to stressful situations in different areas of life. Each statement is evaluated on a Likert response scale indicating the degree of impact and the respondent's ability to deal with the stressor it describes. The instrument was validated with a non-probabilistic sample comprised 450 adults, aged from 18 to 65 years, 62.7% women and 37.3% men, who completed the instrument and also the Perceived Stress Scale, to enable criterion validation. Results Exploratory factor analysis identified 42 valid items and grouped them into eight factors that explained 64.5% of total variance. These factors were financial stressors; working environment stressors; cognitive and behavioral stressors; family environment stressors; health status stressors; stressors related to conditions for relaxation; workload-related stressors; and social relationship stressors. Cronbach's alpha for the instrument was 0.94. A relationship was observed between the newly-developed inventory and the Perceived Stress Scale, providing grounds for accepting the validation hypothesis. Conclusions The results were psychometrically satisfactory and made possible provision of a new instrument for stress interventions, with advantages over other instruments.

Resumo Introdução Muitas pesquisas têm sido realizadas sobre o estresse e seus impactos na saúde das populações. Objetivo Desenvolver e validar um instrumento para identificação dos principais estressores e sua magnitude em pessoas com estresse. Método O instrumento foi construído a partir da análise de 20 entrevistas realizadas com adultos apresentando estresse de acordo com a Escala de Percepção de Estresse (10 homens e 10 mulheres). Um total de 46 afirmativas derivaram desta análise, referindo-se a situações estressantes em diferentes áreas da vida. Cada afirmativa foi avaliada em uma escala do tipo Likert, indicando o grau de impacto e a capacidade do respondente de lidar com o estressor descrito. A validação foi realizada com amostra não probabilística de 450 adultos, com idades entre 18 e 65 anos, 62,7% mulheres e 37,3% homens, que responderam o instrumento e a Escala de Percepção de Estresse, permitindo a validação do critério. Resultados A análise fatorial exploratória identificou 42 itens válidos e os agrupou em oito fatores que explicaram 64,5% da variância total. Esses fatores foram estressores financeiros; do ambiente de trabalho; cognitivos e comportamentais; do ambiente familiar; do estado de saúde; relacionados a condições de relaxamento; relacionados à carga de trabalho; e estressores dos relacionamentos sociais. O alfa de Cronbach para o instrumento foi de 0,94, e observou-se relação entre o inventário desenvolvido e a Escala de Percepção de Estresse, possibilitando a aceitação da hipótese de validação. Conclusões Os resultados foram psicometricamente satisfatórios e possibilitaram a disponibilização de um novo instrumento para intervenções de estresse.

Psychometric properties of the WHOQOL-SRPB BREF, Brazilian Portuguese version

Objective: To test the reliability and the discriminant and convergent validity of the abbreviated Brazilian Portuguese World Health Organization's Quality of Life Instrument - Spirituality, Religion, and Personal Beliefs module (WHOQOL-SRPB BREF). Methods: In a sample of 404 individuals, we applied a general questionnaire, the WHOQOL-BREF, the long-form SRPB, the Brief Religious-Spiritual Coping Scale (RCOPE), and the Beck Depression Inventory (BDI). Priority was given to the 9-item SRPB assessment: its unidimensionality was tested through confirmatory factor analysis and Rasch analysis. Results: Confirmatory factor analysis of the 9-item SRPB assessment indicated an adjusted model with acceptable fit to data. In the Rasch analysis, general fit measures showed adequate performance. The 9-item SRPB assessment showed good internal consistency (alpha = 0.85), and could differentiate (discriminant validity) between religious and atheist/agnostic respondents (mean = 74.7±14.1 and 56.8±15.5, respectively; t = 6.37; degrees of freedom [df] = 402; p < 0.01) and between non-depressed and depressed respondents (mean = 76.5±12.9 and 67.1±16.5; t = 5.57; df = 190.5; p < 0.01). Correlations (convergent validity) were significant with the positive-RCOPE subscale (r = 0.58, p < 0.01) and the WHOQOL-BREF domains (Pearson coefficient ranging between 0.24 and 0.49; p < 0.01), but were in the negative direction with the negative-RCOPE subscale (r = -0.10, p < 0.05). Correlation with the long-form SRPB domain (r = 0.934) was almost perfect. Conclusion: The Brazilian Portuguese 9-item SRPB has good psychometric properties and confirmed the findings of the long-form Brazilian Portuguese version and the abbreviated English version.

Suicidal behavior among substance users: data from the Second Brazilian National Alcohol and Drug Survey (II BNADS)

Objective: To investigate the prevalence rates of suicidal ideation (SI) and suicide attempts (SA) and their association with substance use in a nationally representative sample of Brazilians. Methods: The Second Brazilian National Alcohol and Drug Survey (II BNADS) is a household cross-sectional survey that investigated the consumption of psychotropic drugs and associated risk factors. This national probability sample survey used a multistage cluster design to select 4,607 participants aged 14 or older and had a total response rate of 77%. Illegal drug use, SI and SA were obtained by confidential self-report assessment. Results: SI and SA were reported by 9.9 and 5.4% of the sample, respectively. This prevalence was 20.8 and 12.4% among individuals with alcohol use disorders (AUD), 31.5 and 16.5% among cannabis users and 40.0 and 20.8% among cocaine users. After adjusting for demographic characteristics, tobacco use, family history of suicide and depression, both SI and SA were positively associated with AUD, cannabis and cocaine use. Conclusion: AUD, cannabis and cocaine use were significantly associated with SI and SA, even after the adjustments. Public health initiatives targeting suicide prevention should consider including assessment and management of substance misuse, and therapeutic approaches to substance misuse should include assessment of suicidality.

Psychological morbidity is the main predictor of quality of life among caregivers of individuals in first-episode psychosis: data from a year-long longitudinal study in Brazil

Objective: To investigate quality of life (QoL) and QoL predictors among caregivers of individuals in first-episode psychosis (FEP). Methods: This longitudinal study investigated predictors of QoL in caregivers of 80 individuals in FEP over a 1-year follow-up period, measured using a single component extracted from the 36-item Short-Form Health Survey (SF-36). Results: Mediation analysis demonstrated that, at 1 year, high scores in the Self-Report Questionnaire (SRQ-20) were associated with high scores on the negative sub-scale of the Experience of Caregiving Inventory (ECI), which was also associated with low scores in the Essential Quality of Life (Essential QoL) component extracted from the SEF-36. Clinically, the resulting association indicates that depression and anxiety symptoms in caregivers at baseline are predictors of their 1-year quality of life, based on self-assessment of the caregiving experience. Conclusion: Supporting an individual in FEP can have a negative impact on QoL. Maintaining caregivers' mental health and subjective evaluation of the caregiving experience must be primary goals of FEP services. Complementary studies of FEP caregivers' QoL can support the design of personalized interventions in the near future.

General aspects of quality of life in heterogeneous populations: notes on Flanagan's Quality of Life Scale (QoLS) / Aspectos gerais da qualidade de vida em populações heterogêneas: notas sobre a Escala de Qualidade de Vida de Flanagan

Abstract Introduction: Instruments aimed to investigate general aspects of quality of life are scarce in the literature. Flanagan's Quality of Life Scale (QoLS) is an alternative instrument which provides a more comprehensive evaluation of quality of life in different contexts. Objective: To investigate some psychometric properties of the QoLS and discuss the measurement of quality of life using this scale in heterogeneous and large populations. Methods: The QoLS comprises 16 items divided into five dimensions. Responses were measured using a 7-point rating scale. Data were collected from a stratified sample of primary health care users in the municipality of Ribeirão Preto, state of São Paulo, Brazil. Polychoric correlation matrix and exploratory and confirmatory factor analyses were performed. Results: A total of 1,054 primary health care users in 12 health care facilities were interviewed: 79.7% female; mean age = 36.97 years (standard deviation = 15.1). Moderate to low correlation coefficients were observed between almost all pairs of QoLS items. Items 7 and 9 as well as items 14 and 15 were the pairs presenting the highest correlation coefficient. The original structure of the QoLS, with five dimensions, showed adequate psychometric properties regarding the data collected. The inclusion of a single item on life satisfaction was proposed. Conclusion: The original structure of the QoLS was validated and found to be reliable when applied to primary health care users. A new general item was suggested for future studies to improve the interpretations and associations regarding general aspects of quality of life in large and heterogeneous populations.

Resumo Introdução: Instrumentos destinados a investigar aspectos gerais da qualidade de vida são escassos na literatura. A Escala de Qualidade de Vida de Flanagan (Flanagan's Quality of Life Scale - QoLS) é um instrumento alternativo que fornece uma avaliação mais abrangente da qualidade de vida em diferentes contextos. Objetivo: Investigar propriedades psicométricas da QoLS e discutir a mensuração da qualidade de vida utilizando essa escala em populações amplas e heterogêneas. Métodos: A QoLS é composta de 16 itens divididos em cinco dimensões, cujas categorias de resposta variam em uma escala de 7 pontos. Os dados foram coletados em uma amostra estratificada de usuários da atenção primária do município de Ribeirão Preto, SP. Matriz de correlação policórica e análise fatorial exploratória e confirmatória foram realizadas. Resultados: Foram entrevistados 1.054 usuários da atenção primária em 12 unidades de saúde: 79,7% mulheres; idade média = 36,97 anos (desvio padrão = 15,1). Coeficientes de correlação moderados a baixos foram observados entre quase todos os pares de itens da escala. Os pares de itens 7 e 9, e 14 e 15 foram os que apresentaram o maior coeficiente de correlação. A estrutura original da QoLS, com cinco dimensões, apresentou propriedades psicométricas adequadas em relação aos dados coletados. A inclusão de um item único sobre satisfação com a vida foi proposto. Conclusão: A estrutura original da QoLS foi considerada válida e confiável quando aplicada a usuários da atenção primária. Um novo item geral foi sugerido para estudos futuros, a fim de melhorar as interpretações e associações sobre aspectos gerais da qualidade de vida em populações amplas e heterogêneas.